Pyridazines and derivatives
Medchemexpress LLC Phthalazine | 253-52-1 | 130.15 | 5 G
This organic heterocyclic compound serves as a substrate for human aldehyde oxidase 1, potentially generating reactive oxygen species and leading to enzyme inactivation. It has shown promising activity against various cancers, including blood, breast, colon, lung, and renal cancers.
- Substrate for human aldehyde oxidase 1.
- Nitrogen-containing organic heterocyclic compound.
- Exhibits antitumor activity.
Crescent Chemical Co Inc LUMINOL RESEARCH GRADE
Luminol research grade For microdetermination of superoxide dismutase (2). Peroxidase reagent (1). Size - 5G Storage Conditions - +15 °C TO +30 °C Catalog Number - 28085.02 CAS 521-31-3
Medchemexpress LLC Zardaverine | 101975-10-4 | C12H10F2N2O3 | 50 MG
Zardaverine is an orally active and selective PDE3/4 inhibitor with IC50 values of 0.58 uM for PDE3 and 0.17 uM for PDE4. It exhibits potent bronchodilator activity and is effective in reducing inflammation in asthma. Zardaverine also shows antitumor potential by selectively inhibiting the proliferation of HCC cells, inducing apoptosis, and causing cell cycle arrest (G0/G1 phase).
- Orally active and selective PDE3/4 inhibitor
- Potent bronchodilator activity
- Effective in reducing inflammation in asthma
- Selectively inhibits proliferation of HCC cells
- Induces apoptosis and cell cycle arrest (G0/G1 phase)
- Antitumor potential